Biosafety Cabinets & Laminar Flow Hoods: Ensuring Contamination Control in Critical Workflows

Key Applications

1. Biosafety Cabinets (Class II A2):

• Virology: Handling SARS-CoV-2 cultures with inward airflow (0.38–0.51 m/s) and HEPA-filtered exhaust.

• Cell Therapy: Processing CAR-T cells under aseptic conditions (EU GMP Annex 1 compliance).

• Mycobacteriology: Containing M. tuberculosis via negative-pressure plenums and UV decontamination cycles.

2. Laminar Flow Hoods (Vertical/Horizontal):

• Pharmaceutical Compounding: Preparing IV admixtures in USP <797>-compliant environments.

• Electronics Assembly: Preventing particulate contamination during microchip manufacturing.

• Plant Tissue Culture: Transferring explants under unidirectional airflow (0.45 m/s ±20%).

Technical Specifications & Innovations

Biosafety Cabinet (Class II A2)

• Airflow System:

  • 30% recirculated + 70% exhausted HEPA (H14) airflow

  • Inflow velocity: 0.53 m/s ±0.025 (EN 12469:2000 validated)

• Filtration:

  • Dual ULPA filters (99.9995% @ 0.12μm) for exhaust

  • Optional germicidal UV-C (254 nm) with 25 μW/cm² irradiance

• Ergonomics:

  • Anti-glide sash with 8–18 inch working height

  • Foot-operated electrical outlets (IEC 61010-1 compliant)

Laminar Flow Hood (Vertical)

• Airflow Design:

  • Unidirectional vertical flow (0.3–0.5 m/s) over 0.24 m² workspace

  • Pre-filter (G4) + HEPA (H13) filtration (99.95% @ 0.3μm)

• Construction:

  • 304 stainless steel interior (Ra ≤0.8 μm roughness)

  • Seamless curved corners for CIP (Clean-in-Place) compliance

• Monitoring:

  • Magnehelic gauge (±5% accuracy) for filter load tracking

  • Real-time particle counter (ISO 14644-1 Class 5)