High-Speed Refrigerated Centrifuge: Precision Engineering for Advanced Bioseparation

Applications in Detail

• Vaccine Development: Ultracentrifugation (up to 100,000×g) is employed to purify viral vectors (e.g., adenovirus) for mRNA vaccine production.

• Proteomics Research: Differential centrifugation separates organelles (mitochondria, lysosomes) for protein profiling via 2D gel electrophoresis.

• Clinical Diagnostics: Rapid isolation of platelet-rich plasma (PRP) for regenerative medicine, complying with AABB standards.

Technical Specifications

• Motor System: Brushless DC motor with adaptive torque control, achieving 0–30,000 RPM in 90 seconds (energy efficiency: <1.5 kW/h).

• Refrigeration: Dual-stage Peltier cooling maintains -20°C to +40°C (±0.5°C) even at maximum RPM.

• Rotor Options: Titanium swing-out rotors (max RCF 65,000×g) for 50 mL conical tubes; certified for biohazard containment (BSL-2).

• Safety Features: HERMLE-certified lid locks, imbalance sensors, and IEC 61010-2-020 compliance for electrical safety.

Industry Compliance & Validation

• Validated per FDA 21 CFR Part 11 for electronic records in GMP environments.

• CE-IVDR certified for in-vitro diagnostic use, including traceability via RFID rotor identification.

Case Study
A biopharma lab utilized the centrifuge for exosome isolation from stem cell cultures. By optimizing protocols (18,000 RPM, 4°C, 45 minutes), they achieved 95% purity (confirmed via nanoparticle tracking analysis).